PrimePCR™ Probe Assay: COL11A1, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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PrimePCR™ PreAmp for Probe Assay: COL11A1, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: COL11A1, Human
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


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Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCIP0027016
Assay Design:   Intron-spanning
Chromosome Location:   1:103484389-103488316question
Amplicon Length:   78
Splice Variants Targeted:   ENST00000370096 ENST00000512756 ENST00000427239 ENST00000358392 ENST00000353414 ENST00000370090

Gene Information

This gene encodes one of the two alpha chains of type XI collagen a minor fibrillar collagen. Type XI collagen is a heterotrimer but the third alpha chain is a post-translationally modified alpha 1 type II chain. Mutations in this gene are associated with type II Stickler syndrome and with Marshall syndrome. A single-nucleotide polymorphism in this gene is also associated with susceptibility to lumbar disc herniation. Multiple transcript variants have been identified for this gene. [provided by RefSeq Nov 2009]

Gene Symbol:   COL11A1
Gene Name:   collagen, type XI, alpha 1
Aliases:   CO11A1, COLL6, STL2
RefSeq:   NC_000001.10 NT_032977.9 NG_008033.1
Ensembl:   ENSG00000060718
Entrez:   1301
Chromosome Mapping:   1p21

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