PrimePCR™ Probe Assay: INPP5B, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

List Price:    $263.00
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Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCIP0027116
Assay Design:   Intron-spanning
Chromosome Location:   1:38351408-38352622question
Amplicon Length:   123
Splice Variants Targeted:   ENST00000373027 ENST00000373026 ENST00000373024 ENST00000373023 ENST00000373029

Gene Information

Cellular calcium signaling is controlled by the production of inositol phosphates (IPs) by phospholipase C in response to extracellular signals. The IP signaling molecules are inactivated by a family of inositol polyphosphate-5-phosphatases (5-phosphatases). This gene encodes the type II 5-phosphatase. The protein is localized to the cytosol and mitochondria and associates with membranes through an isoprenyl modification near the C-terminus. Several alternatively spliced transcript variants of this gene have been described but the full-length nature of some of these variants has not been determined. [provided by RefSeq Jul 2008]

Gene Symbol:   INPP5B
Gene Name:   inositol polyphosphate-5-phosphatase, 75kDa
Aliases:   5PTase, MGC65156, MGC71303
RefSeq:   NC_000001.10 NT_032977.9
Ensembl:   ENSG00000204084
Entrez:   3633
Chromosome Mapping:   1p34

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