PrimePCR™ Probe Assay: ENG, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

List Price:    $263.00
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PrimePCR™ PreAmp for Probe Assay: ENG, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: ENG, Human
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCIP0027737
Assay Design:   Intron-spanning
Chromosome Location:   9:130581010-130582191question
Amplicon Length:   124
Splice Variants Targeted:   ENST00000373203 ENST00000344849 ENST00000545345 ENST00000546301

Gene Information

This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds TGFB1 and TGFB3 with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia also known as Osler-Rendu-Weber syndrome 1 an autosomal dominant multisystemic vascular dysplasia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq Sep 2008]

Gene Symbol:   ENG
Gene Name:   endoglin
Aliases:   CD105, END, FLJ41744, HHT1, ORW, ORW1
RefSeq:   NC_000009.11 NG_009551.1 NG_023245.1 NT_008470.19
Ensembl:   ENSG00000106991
Entrez:   2022
Chromosome Mapping:   9q33-q34.1

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