PrimePCR™ Probe Assay: TPD52L1, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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PrimePCR™ PreAmp for Probe Assay: TPD52L1, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: TPD52L1, Human
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCIP0027793
Assay Design:   Intron-spanning
Chromosome Location:   6:125541266-125550365question
Amplicon Length:   146
Splice Variants Targeted:   ENST00000534368 ENST00000304877 ENST00000534000 ENST00000368402 ENST00000368388 ENST00000527711 ENST00000528193 ENST00000532429 ENST00000534199 ENST00000392482 ENST00000524679 ENST00000392484

Gene Information

This gene encodes a member of the tumor protein D52 (TPD52) family. The encoded protein contains a coiled-coil domain and may form homo- or hetero-dimer with TPD52 family members. The protein is reported to be involved in cell proliferation and calcium signaling. It also interacts with the mitogen-activated protein kinase kinase kinase 5 (MAP3K5/ASK1) and positively regulates MAP3K5-induced apoptosis. Multiple alternatively spliced transcript variants have been observed but the full-length nature of some variants has not yet been determined. [provided by RefSeq Jul 2008]

Gene Symbol:   TPD52L1
Gene Name:   tumor protein D52-like 1
Aliases:   D53, MGC8556, TPD52L2, hD53
RefSeq:   NC_000006.11 NT_025741.15
Ensembl:   ENSG00000111907
Entrez:   7164
Chromosome Mapping:   6q22-q23

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