PrimePCR™ Probe Assay: PTPRN, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCIP0027800
Assay Design:   Intron-spanning
Chromosome Location:   2:220168482-220172193question
Amplicon Length:   70
Splice Variants Targeted:   ENST00000409251 ENST00000295718 ENST00000412847 ENST00000446182 ENST00000440552 ENST00000442029 ENST00000451506 ENST00000539342 ENST00000537666 ENST00000536579

Gene Information

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth differentiation mitotic cycle and oncogenic transformation. This PTP possesses an extracellular region a single transmembrane region and a single catalytic domain and thus represents a receptor-type PTP. This PTP was found to be an autoantigen that is reactive with insulin-dependent diabetes mellitus (IDDM) patient sera and thus may be a potential target of autoimmunity in diabetes mellitus. Alternate splicing results in multiple transcript variants.[provided by RefSeq Dec 2010]

Gene Symbol:   PTPRN
Gene Name:   protein tyrosine phosphatase, receptor type, N
Aliases:   FLJ16131, IA-2, IA-2/PTP, IA2, ICA512, R-PTP-N
RefSeq:   NC_000002.11 NT_005403.17
Ensembl:   ENSG00000054356
Entrez:   5798
Chromosome Mapping:   2q35-q36.1

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