PrimePCR™ Probe Assay: SNAI2, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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PrimePCR™ PreAmp for Probe Assay: SNAI2, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: SNAI2, Human
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCIP0027976
Assay Design:   Intron-spanning
Chromosome Location:   8:49832926-49833829question
Amplicon Length:   129
Splice Variants Targeted:   ENST00000396822 ENST00000020945

Gene Information

This gene encodes a member of the Snail family of C2H2-type zinc finger transcription factors. The encoded protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma. This protein is involved in epithelial-mesenchymal transitions and has antiapoptotic activity. Mutations in this gene may be associated with sporatic cases of neural tube defects. [provided by RefSeq Jul 2008]

Gene Symbol:   SNAI2
Gene Name:   snail homolog 2 (Drosophila)
Aliases:   MGC10182, SLUG, SLUGH1, WS2D
RefSeq:   NC_000008.10 NG_012130.1 NT_008183.19
Ensembl:   ENSG00000019549
Entrez:   6591
Chromosome Mapping:   8q11

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