PrimePCR™ Probe Assay: CES2, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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PrimePCR™ PreAmp for Probe Assay: CES2, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: CES2, Human
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCIP0028107
Assay Design:   Intron-spanning
Chromosome Location:   16:66972081-66973186question
Amplicon Length:   101
Splice Variants Targeted:   ENST00000317091 ENST00000417689

Gene Information

This gene encodes a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics such as cocaine and heroin and endogenous substrates with ester thioester or amide bonds. They may participate in fatty acyl and cholesterol ester metabolism and may play a role in the blood-brain barrier system. The protein encoded by this gene is the major intestinal enzyme and functions in intestine drug clearance. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq Oct 2010]

Gene Symbol:   CES2
Gene Name:   carboxylesterase 2
Aliases:   CE-2, CES2A1, PCE-2, iCE
RefSeq:   NC_000016.9 NT_010498.15
Ensembl:   ENSG00000172831
Entrez:   8824
Chromosome Mapping:   16q22.1

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