PrimePCR™ Probe Assay: EDNRB, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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PrimePCR™ PreAmp for Probe Assay: EDNRB, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: EDNRB, Human
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


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Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCIP0028156
Assay Design:   Intron-spanning
Chromosome Location:   13:78474054-78474773question
Amplicon Length:   137
Splice Variants Targeted:   ENST00000377211 ENST00000334286 ENST00000446573

Gene Information

The protein encoded by this gene is a G protein-coupled receptor which activates a phosphatidylinositol-calcium second messenger system. Its ligand endothelin consists of a family of three potent vasoactive peptides: ET1 ET2 and ET3. Studies suggest that the multigenic disorder Hirschsprung disease type 2 is due to mutations in the endothelin receptor type B gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq Jan 2011]

Gene Symbol:   EDNRB
Gene Name:   endothelin receptor type B
Aliases:   ABCDS, ETB, ETBR, ETRB, HSCR, HSCR2, WS4A
RefSeq:   NC_000013.10 NG_011630.2 NT_024524.14
Ensembl:   ENSG00000136160
Entrez:   1910
Chromosome Mapping:   13q22

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