PrimePCR™ Probe Assay: JAK3, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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PrimePCR™ PreAmp for Probe Assay: JAK3, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: JAK3, Human
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


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Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCIP0028483
Assay Design:   Intron-spanning
Chromosome Location:   19:17943705-17945440question
Amplicon Length:   65
Splice Variants Targeted:   ENST00000527670 ENST00000534444 ENST00000458235

Gene Information

The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease). [provided by RefSeq Jul 2008]

Gene Symbol:   JAK3
Gene Name:   Janus kinase 3
Aliases:   JAK-3, JAK3_HUMAN, JAKL, L-JAK, LJAK
RefSeq:   NC_000019.9 NG_007273.1 NG_012092.1 NT_011295.11
Ensembl:   ENSG00000105639
Entrez:   3718
Chromosome Mapping:   19p13.1

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