PrimePCR™ Probe Assay: TNFAIP3, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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PrimePCR™ PreAmp for Probe Assay: TNFAIP3, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: TNFAIP3, Human
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCIP0028538
Assay Design:   Intron-spanning
Chromosome Location:   6:138192596-138196069question
Amplicon Length:   122
Splice Variants Targeted:   ENST00000420009 ENST00000237289 ENST00000535574 ENST00000544646 ENST00000535332 ENST00000539356 ENST00000536070

Gene Information

This gene was identified as a gene whose expression is rapidly induced by the tumor necrosis factor (TNF). The protein encoded by this gene is a zinc finger protein and has been shown to inhibit NF-kappa B activation as well as TNF-mediated apoptosis. Knockout studies of a similar gene in mice suggested that this gene is critical for limiting inflammation by terminating TNF-induced NF-kappa B responses. [provided by RefSeq Jul 2008]

Gene Symbol:   TNFAIP3
Gene Name:   tumor necrosis factor, alpha-induced protein 3
Aliases:   A20, MGC104522, MGC138687, MGC138688, OTUD7C, TNFA1P2
RefSeq:   NC_000006.11 NT_025741.15
Ensembl:   ENSG00000118503
Entrez:   7128
Chromosome Mapping:   6q23

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