PrimePCR™ Probe Assay: PEA15, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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PrimePCR™ PreAmp for Probe Assay: PEA15, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: PEA15, Human
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCIP0028759
Assay Design:   Intron-spanning
Chromosome Location:   1:160181476-160183037question
Amplicon Length:   139
Splice Variants Targeted:   ENST00000360472 ENST00000368076

Gene Information

This gene encodes a death effector domain-containing protein which is a major phosphoprotein in astrocytes and an endogenous substrate for protein kinase C. Studies using knockout mice suggest that this protein may protect astrocytes from TNF-induced apoptosis. This protein is also overexpressed in type 2 diabetes mellitus where it may contribute to insulin resistance in glucose uptake. [provided by RefSeq Sep 2011]

Gene Symbol:   PEA15
Gene Name:   phosphoprotein enriched in astrocytes 15
Aliases:   HMAT1, HUMMAT1H, MAT1, MAT1H, PEA-15, PED
RefSeq:   NC_000001.10 NT_004487.19
Ensembl:   ENSG00000162734
Entrez:   8682
Chromosome Mapping:   1q21.1

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