PrimePCR™ Probe Assay: TIMM8B, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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PrimePCR™ PreAmp for Probe Assay: TIMM8B, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: TIMM8B, Human
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCIP0029081
Assay Design:   Intron-spanning
Chromosome Location:   11:111956108-111957464question
Amplicon Length:   150
Splice Variants Targeted:   ENST00000504148 ENST00000541231

Gene Information

This gene encodes a member of a well-conserved family of proteins with similarity to yeast Tim mitochondrial import proteins. This gene is encoded by a nuclear gene and is transported into the intermembrane space of the mitochondrion. When formed into complexes these proteins guide membrane-spanning proteins across the mitochondrial intermembrane space before they are added into the mitochondrial inner membrane. This gene is adjacent to succinate dehydrogenase subunit D (SDHD) in which mutations have been found in affected members of families with hereditary paraganglioma.[provided by RefSeq Aug 2009]

Gene Symbol:   TIMM8B
Gene Name:   translocase of inner mitochondrial membrane 8 homolog B (yeast)
Aliases:   DDP2, FLJ21744, MGC102866, MGC117373, TIM8B
RefSeq:   NC_000011.9 NG_012337.1 NT_033899.8
Ensembl:   ENSG00000150779
Entrez:   26521
Chromosome Mapping:   11q23.1-q23.2

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