PrimePCR™ Probe Assay: KCNE3, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCIP0029229
Assay Design:   Intron-spanning
Chromosome Location:   11:74168562-74173132question
Amplicon Length:   190
Splice Variants Targeted:   ENST00000310128 ENST00000525550 ENST00000532569 ENST00000531854 ENST00000529425 ENST00000526855

Gene Information

Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release heart rate insulin secretion neuronal excitability epithelial electrolyte transport smooth muscle contraction and cell volume. This gene encodes a member of the potassium channel voltage-gated isk-related subfamily. This member is a type I membrane protein and a beta subunit that assembles with a potassium channel alpha-subunit to modulate the gating kinetics and enhance stability of the multimeric complex. This gene is prominently expressed in the kidney. A missense mutation in this gene is associated with hypokalemic periodic paralysis. [provided by RefSeq Jul 2008]

Gene Symbol:   KCNE3
Gene Name:   potassium voltage-gated channel, Isk-related family, member 3
Aliases:   DKFZp781H21101, HOKPP, HYPP, MGC102685, MGC129924, MiRP2
RefSeq:   NC_000011.9 NG_011833.1 NT_167190.1
Ensembl:   ENSG00000175538
Entrez:   10008
Chromosome Mapping:   11q13.4

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