PrimePCR™ Probe Assay: STAB2, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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PrimePCR™ PreAmp for Probe Assay: STAB2, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: STAB2, Human
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCIP0029537
Assay Design:   Intron-spanning
Chromosome Location:   12:104067808-104069795question
Amplicon Length:   118
Splice Variants Targeted:   ENST00000388887 ENST00000258495

Gene Information

This gene encodes a large transmembrane receptor protein which may function in angiogenesis lymphocyte homing cell adhesion or receptor scavenging. The protein contains 7 fasciclin 15 epidermal growth factor (EGF)-like and 2 laminin-type EGF-like domains as well as a C-type lectin-like hyaluronan-binding Link module. The protein is primarily expressed on sinusoidal endothelial cells of liver spleen and lymph node. The receptor has been shown to bind and endocytose ligands such as hyaluronan low density lipoprotein Gram-positive and Gram-negative bacteria and advanced glycosylation end products. Supporting its possible role as a scavenger receptor the protein has been shown to cycle between the plasma membrane and lysosomes. [provided by RefSeq Jul 2008]

Gene Symbol:   STAB2
Gene Name:   stabilin 2
Aliases:   DKFZp434E0321, FEEL2, FELE-2, FELL2, FEX2, HARE
RefSeq:   NC_000012.11 NT_029419.12
Ensembl:   ENSG00000136011
Entrez:   55576
Chromosome Mapping:   12q23.3

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