PrimePCR™ Probe Assay: IRF8, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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PrimePCR™ PreAmp for Probe Assay: IRF8, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: IRF8, Human
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCIP0029839
Assay Design:   Intron-spanning
Chromosome Location:   16:85942654-85945209question
Amplicon Length:   130
Splice Variants Targeted:   ENST00000268638

Gene Information

Interferon consensus sequence-binding protein (ICSBP) is a transcription factor of the interferon (IFN) regulatory factor (IRF) family. Proteins of this family are composed of a conserved DNA-binding domain in the N-terminal region and a divergent C-terminal region that serves as the regulatory domain. The IRF family proteins bind to the IFN-stimulated response element (ISRE) and regulate expression of genes stimulated by type I IFNs namely IFN-alpha and IFN-beta. IRF family proteins also control expression of IFN-alpha and IFN-beta-regulated genes that are induced by viral infection. [provided by RefSeq Jul 2008]

Gene Symbol:   IRF8
Gene Name:   interferon regulatory factor 8
Aliases:   H-ICSBP, ICSBP, ICSBP1, IRF-8
RefSeq:   NC_000016.9 NT_010498.15
Ensembl:   ENSG00000140968
Entrez:   3394
Chromosome Mapping:   16q24.1

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