PrimePCR™ Probe Assay: LUM, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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PrimePCR™ PreAmp for Probe Assay: LUM, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: LUM, Human
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCIP0029895
Assay Design:   Intron-spanning
Chromosome Location:   12:91497979-91501948question
Amplicon Length:   142
Splice Variants Targeted:   ENST00000266718

Gene Information

This gene encodes a member of the small leucine-rich proteoglycan (SLRP) family that includes decorin biglycan fibromodulin keratocan epiphycan and osteoglycin. In these bifunctional molecules the protein moiety binds collagen fibrils and the highly charged hydrophilic glycosaminoglycans regulate interfibrillar spacings. Lumican is the major keratan sulfate proteoglycan of the cornea but is also distributed in interstitial collagenous matrices throughout the body. Lumican may regulate collagen fibril organization and circumferential growth corneal transparency and epithelial cell migration and tissue repair. [provided by RefSeq Jul 2008]

Gene Symbol:   LUM
Gene Name:   lumican
Aliases:   LDC, SLRR2D
RefSeq:   NC_000012.11 NT_029419.12
Ensembl:   ENSG00000139329
Entrez:   4060
Chromosome Mapping:   12q21.3-q22

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