PrimePCR™ Probe Assay: SLC5A8, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCIP0029977
Assay Design:   Intron-spanning
Chromosome Location:   12:101598296-101603390question
Amplicon Length:   133
Splice Variants Targeted:   ENST00000536262

Gene Information

SLC5A8 has been shown to transport iodide by a passive mechanism (Rodriguez et al. 2002 [PubMed 12107270]) and monocarboxylates and short-chain fatty acids by a sodium-coupled mechanism (Gopal et al. 2004 [PubMed 15322102]). In kidney SLC5A8 functions as a high-affinity sodium-coupled lactate transporter involved in reabsorption of lactate and maintenance of blood lactate levels (Thangaraju et al. 2006 [PubMed 16873376]).[supplied by OMIM Dec 2008]

Gene Symbol:   SLC5A8
Gene Name:   solute carrier family 5 (iodide transporter), member 8
Aliases:   AIT, MGC125354, SMCT, SMCT1
RefSeq:   NC_000012.11 NT_029419.12 NW_003315942.1
Ensembl:   ENSG00000256870
Entrez:   160728
Chromosome Mapping:   12q23.1

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