PrimePCR™ Probe Assay: HMGN3, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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PrimePCR™ PreAmp for Probe Assay: HMGN3, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: HMGN3, Human
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCIP0030359
Assay Design:   Intron-spanning
Chromosome Location:   6:79913337-79944322question
Amplicon Length:   122
Splice Variants Targeted:   ENST00000344726 ENST00000275036

Gene Information

Thyroid hormone receptors are hormone-dependent transcription factors that regulate expression of a variety of specific target genes. The protein encoded by this gene binds thyroid hormone receptor beta but only in the presence of thyroid hormone. The encoded protein a member of the HMGN protein family is thought to reduce the compactness of the chromatin fiber in nucleosomes thereby enhancing transcription from chromatin templates. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq Jan 2011]

Gene Symbol:   HMGN3
Gene Name:   high mobility group nucleosomal binding domain 3
Aliases:   DKFZp686E20226, FLJ42187, PNAS-25, TRIP7
RefSeq:   NC_000006.11 NT_007299.13
Ensembl:   ENSG00000118418
Entrez:   9324
Chromosome Mapping:   6q14.1

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