PrimePCR™ Probe Assay: SLC18A2, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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PrimePCR™ PreAmp for Probe Assay: SLC18A2, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: SLC18A2, Human
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCIP0030748
Assay Design:   Intron-spanning
Chromosome Location:   10:119001242-119003532question
Amplicon Length:   105
Splice Variants Targeted:   ENST00000298472

Gene Information

The vesicular monoamine transporter acts to accumulate cytosolic monoamines into synaptic vesicles using the proton gradient maintained across the synaptic vesicular membrane. Its proper function is essential to the correct activity of the monoaminergic systems that have been implicated in several human neuropsychiatric disorders. The transporter is a site of action of important drugs including reserpine and tetrabenazine (summary by Peter et al. 1993 [PubMed 7905859]). See also SLC18A1 (MIM 193002).[supplied by OMIM Jan 2011]

Gene Symbol:   SLC18A2
Gene Name:   solute carrier family 18 (vesicular monoamine), member 2
Aliases:   MGC120477, MGC120478, MGC26538, SVAT, SVMT, VAT2, VMAT2
RefSeq:   NC_000010.10 NT_030059.13
Ensembl:   ENSG00000165646
Entrez:   6571
Chromosome Mapping:   10q25

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