PrimePCR™ Probe Assay: GIPR, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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PrimePCR™ PreAmp for Probe Assay: GIPR, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: GIPR, Human
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCIP0031266
Assay Design:   Intron-spanning
Chromosome Location:   19:46176151-46177379question
Amplicon Length:   80
Splice Variants Targeted:   ENST00000263281 ENST00000304207

Gene Information

This gene encodes a G-protein coupled receptor for gastric inhibitory polypeptide (GIP) which was originally identified as an activity in gut extracts that inhibited gastric acid secretion and gastrin release but subsequently was demonstrated to stimulate insulin release in the presence of elevated glucose. Mice lacking this gene exhibit higher blood glucose levels with impaired initial insulin response after oral glucose load. Defect in this gene thus may contribute to the pathogenesis of diabetes. [provided by RefSeq Oct 2011]

Gene Symbol:   GIPR
Gene Name:   gastric inhibitory polypeptide receptor
Aliases:   MGC126722, PGQTL2
RefSeq:   NC_000019.9 NT_011109.16
Ensembl:   ENSG00000010310
Entrez:   2696
Chromosome Mapping:   19q13.3

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