PrimePCR™ Probe Assay: MERTK, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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PrimePCR™ PreAmp for Probe Assay: MERTK, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: MERTK, Human
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCIP0031506
Assay Design:   Intron-spanning
Chromosome Location:   2:112758833-112760751question
Amplicon Length:   84
Splice Variants Targeted:   ENST00000295408 ENST00000409780 ENST00000421804 ENST00000393237

Gene Information

This gene is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains two Ig-like C2-type (immunoglobulin-like) domains and one tyrosine kinase domain. Mutations in this gene have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa (RP). [provided by RefSeq Jul 2008]

Gene Symbol:   MERTK
Gene Name:   c-mer proto-oncogene tyrosine kinase
Aliases:   MER, MGC133349, RP38, c-mer
RefSeq:   NC_000002.11 NG_011607.1 NT_022135.16
Ensembl:   ENSG00000153208
Entrez:   10461
Chromosome Mapping:   2q14.1

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