PrimePCR™ Probe Assay: XDH, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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PrimePCR™ PreAmp for Probe Assay: XDH, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: XDH, Human
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCIP0031777
Assay Design:   Intron-spanning
Chromosome Location:   2:31609332-31610763question
Amplicon Length:   147
Splice Variants Targeted:   ENST00000379416

Gene Information

Xanthine dehydrogenase belongs to the group of molybdenum-containing hydroxylases involved in the oxidative metabolism of purines. The enzyme is a homodimer. Xanthine dehydrogenase can be converted to xanthine oxidase by reversible sulfhydryl oxidation or by irreversible proteolytic modification. Defects in xanthine dehydrogenase cause xanthinuria may contribute to adult respiratory stress syndrome and may potentiate influenza infection through an oxygen metabolite-dependent mechanism. [provided by RefSeq Jul 2008]

Gene Symbol:   XDH
Gene Name:   xanthine dehydrogenase
Aliases:   XO, XOR
RefSeq:   NC_000002.11 NG_008871.1 NT_022184.15
Ensembl:   ENSG00000158125
Entrez:   7498
Chromosome Mapping:   2p23.1

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