PrimePCR™ Probe Assay: IRAK3, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCIP0031947
Assay Design:   Intron-spanning
Chromosome Location:   12:66622107-66638387question
Amplicon Length:   136
Splice Variants Targeted:   ENST00000261233 ENST00000457197

Gene Information

This gene encodes a member of the interleukin-1 receptor-associated kinase protein family. Members of this family are essential components of the Toll/IL-R immune signal transduction pathways. This protein is primarily expressed in monocytes and macrophages and functions as a negative regulator of Toll-like receptor signaling. Mutations in this gene are associated with a susceptibility to asthma. Alternate splicing results in multiple transcript variants. [provided by RefSeq May 2010]

Gene Symbol:   IRAK3
Gene Name:   interleukin-1 receptor-associated kinase 3
Aliases:   ASRT5, FLJ13601, IRAKM
RefSeq:   NC_000012.11 NT_029419.12 NG_021194.1
Ensembl:   ENSG00000090376
Entrez:   11213
Chromosome Mapping:   12q14.3

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