PrimePCR™ Probe Assay: RUNX1, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

List Price:    $263.00
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PrimePCR™ PreAmp for Probe Assay: RUNX1, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: RUNX1, Human
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


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Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCIP0040541
Assay Design:   Intron-spanning
Chromosome Location:   21:36231849-36252930question
Amplicon Length:   74
Splice Variants Targeted:   ENST00000486278 ENST00000325074 ENST00000437180 ENST00000399237 ENST00000358356 ENST00000399240 ENST00000300305 ENST00000344691

Gene Information

Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well-documented and have been associated with several types of leukemia. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq Jul 2008]

Gene Symbol:   RUNX1
Gene Name:   runt-related transcription factor 1
Aliases:   AML1, AML1-EVI-1, AMLCR1, CBFA2, EVI-1, PEBP2aB
RefSeq:   NC_000021.8 NT_011512.11 NG_011402.1
Ensembl:   ENSG00000159216
Entrez:   861
Chromosome Mapping:   21q22.3

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