PrimePCR™ Probe Assay: MAP4, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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PrimePCR™ PreAmp for Probe Assay: MAP4, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: MAP4, Human
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCIP0041626
Assay Design:   Intron-spanning
Chromosome Location:   3:47896794-47908739question
Amplicon Length:   112
Splice Variants Targeted:   ENST00000429422 ENST00000395734 ENST00000426837 ENST00000360240 ENST00000420772 ENST00000335271 ENST00000441748 ENST00000383737 ENST00000264724

Gene Information

The protein encoded by this gene is a major non-neuronal microtubule-associated protein. This protein contains a domain similar to the microtubule-binding domains of neuronal microtubule-associated protein (MAP2) and microtubule-associated protein tau (MAPT/TAU). This protein promotes microtubule assembly and has been shown to counteract destabilization of interphase microtubule catastrophe promotion. Cyclin B was found to interact with this protein which targets cell division cycle 2 (CDC2) kinase to microtubules. The phosphorylation of this protein affects microtubule properties and cell cycle progression. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq Aug 2008]

Gene Symbol:   MAP4
Gene Name:   microtubule-associated protein 4
Aliases:   DKFZp779A1753, MGC8617
RefSeq:   NC_000003.11 NT_022517.18
Ensembl:   ENSG00000047849
Entrez:   4134
Chromosome Mapping:   3p21

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