PrimePCR™ lncRNA® Probe Assay:CENPB, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression.

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   Same primer pair as used in SYBR assay qhsaLED0103531

List Price:    $268.00
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PrimePCR™ IncRNA PreAmp for Probe Assay: CENPB, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ IncRNA Template for Probe Assay: CENPB, Human
Reaction:     4 billion copies/200 µl
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   lncRNA Expression
Unique Assay ID:   qhsaLEP0180771
Assay Design:   exonic
Chromosome Location:   chr20:3786246-3786376question
Amplicon Length:   101
Refseq Transcripts Amplified:   NM_001810
Splice Variants Targeted:   ENST00000379751
LNCipedia Splice Variants Targeted:   lnc-SPEF1-1:1

Gene Information

This gene product is a highly conserved protein that facilitates centromere formation. It is a DNA-binding protein that is derived from transposases of the pogo DNA transposon family. It contains a helix-loop-helix DNA binding motif at the N-terminus and a dimerization domain at the C-terminus. The DNA binding domain recognizes and binds a 17-bp sequence (CENP-B box) in the centromeric alpha satellite DNA. This protein is proposed to play an important role in the assembly of specific centromere structures in interphase nuclei and on mitotic chromosomes. It is also considered a major centromere autoantigen recognized by sera from patients with anti-centromere antibodies. [provided by RefSeq Jul 2008]

Gene Symbol:   CENPB
Gene Name:   centromere protein B, 80kDa
Aliases:   Not Available
RefSeq:   NC_000020.10 NT_011387.8
Ensembl:   ENSG00000125817
LNCipedia:   lnc-SPEF1-1
Entrez:   1059
Chromosome Mapping:   20p13
Gene Strand:   Not Available

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