PrimePCR™ lncRNA® Probe Assay:CDK8, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression.

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   Same primer pair as used in SYBR assay qhsaLED0103871

List Price:    $247.00
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PrimePCR™ IncRNA PreAmp for Probe Assay: CDK8, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ IncRNA Template for Probe Assay: CDK8, Human
Reaction:     4 billion copies/200 µl
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   lncRNA Expression
Unique Assay ID:   qhsaLEP0181111
Assay Design:   exonic
Chromosome Location:   chr13:26405000-26405095question
Amplicon Length:   66
Splice Variants Targeted:   ENST00000381527 ENST00000536792 ENST00000480323 ENST00000477277
LNCipedia Splice Variants Targeted:   lnc-WASF3-2:1

Gene Information

The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28 and Schizosaccharomyces pombe cdc2 and are known to be important regulators of cell cycle progression. This kinase and its regulatory subunit cyclin C are components of the RNA polymerase II holoenzyme complex which phosphorylates the carboxy-terminal domain (CTD) of the largest subunit of RNA polymerase II. This kinase has also been shown to regulate transcription by targeting the CDK7/cyclin H subunits of the general transcription initiation factor IIH (TFIIH) thus providing a link between the 'Mediator-like' protein complexes and the basal transcription machinery. [provided by RefSeq Jul 2008]

Gene Symbol:   CDK8
Gene Name:   cyclin-dependent kinase 8
Aliases:   K35, MGC126074, MGC126075
RefSeq:   NC_000013.10 NT_024524.14
Ensembl:   ENSG00000132964
LNCipedia:   lnc-WASF3-2
Entrez:   1024
Chromosome Mapping:   13q12
Gene Strand:   Not Available

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