PrimePCR™ lncRNA® Probe Assay:ABCG2, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression.

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   Same primer pair as used in SYBR assay qhsaLED0104045

List Price:    $247.00
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PrimePCR™ IncRNA PreAmp for Probe Assay: ABCG2, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ IncRNA Template for Probe Assay: ABCG2, Human
Reaction:     4 billion copies/200 µl
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   lncRNA Expression
Unique Assay ID:   qhsaLEP0181285
Assay Design:   exonic
Chromosome Location:   chr4:88139807-88139933question
Amplicon Length:   97
Refseq Transcripts Amplified:   NM_001257386,NM_004827,XM_005263355,XM_011532420,XM_017008853,XM_017008852,XM_005263354,XM_005263356
Splice Variants Targeted:   ENST00000505480 ENST00000237612 ENST00000503830 ENST00000515655
LNCipedia Splice Variants Targeted:   lnc-PPM1K-3:1

Gene Information

The membrane-associated protein encoded by this gene is included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1 MDR/TAP MRP ALD OABP GCN20 White). This protein is a member of the White subfamily. Alternatively referred to as a breast cancer resistance protein this protein functions as a xenobiotic transporter which may play a major role in multi-drug resistance. It likely serves as a cellular defense mechanism in response to mitoxantrone and anthracycline exposure. Significant expression of this protein has been observed in the placenta which may suggest a potential role for this molecule in placenta tissue. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq Apr 2012]

Gene Symbol:   ABCG2
Gene Name:   ATP-binding cassette, sub-family G (WHITE), member 2
Aliases:   ABC15, ABCP, BCRP, BCRP1, BMDP, CD338, CDw338, EST157481, MGC102821, MRX, MXR, MXR1
RefSeq:   NC_000004.11 NT_016354.19
Ensembl:   ENSG00000118777
LNCipedia:   lnc-PPM1K-3
Entrez:   9429
Chromosome Mapping:   4q22
Gene Strand:   Not Available

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