PrimePCR™ lncRNA® Probe Assay:ADAMTS5, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression.

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   Same primer pair as used in SYBR assay qhsaLED0133665. May amplify unspliced transcripts of an antisense gene.

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PrimePCR™ IncRNA PreAmp for Probe Assay: ADAMTS5, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ IncRNA Template for Probe Assay: ADAMTS5, Human
Reaction:     4 billion copies/200 µl
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   lncRNA Expression
Unique Assay ID:   qhsaLEP0210905
Assay Design:   exonic
Chromosome Location:   chr21:26919251-26919399question
Amplicon Length:   119
Refseq Transcripts Amplified:   NM_007038,XM_011529448
Splice Variants Targeted:   ENST00000284987
LNCipedia Splice Variants Targeted:   lnc-ADAMTS1-2:1

Gene Information

This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules including a propeptide region a metalloproteinase domain a disintegrin-like domain and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs and some have unique C-terminal domains. The enzyme encoded by this gene contains two C-terminal TS motifs and functions as aggrecanase to cleave aggrecan a major proteoglycan of cartilage. [provided by RefSeq Jul 2008]

Gene Symbol:   ADAMTS5
Gene Name:   ADAM metallopeptidase with thrombospondin type 1 motif, 5
Aliases:   ADAMTS11, ADMP-2, FLJ36738
RefSeq:   NC_000021.8 NT_011512.11
Ensembl:   ENSG00000154736
LNCipedia:   lnc-ADAMTS1-2
Entrez:   11096
Chromosome Mapping:   21q21.3
Gene Strand:   Not Available

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