PrimePCR™ lncRNA® Probe Assay:FOXP2, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression.

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   Same primer pair as used in SYBR assay qhsaLED0219761

List Price:    $247.00
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PrimePCR™ IncRNA PreAmp for Probe Assay: FOXP2, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ IncRNA Template for Probe Assay: FOXP2, Human
Reaction:     4 billion copies/200 µl
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   lncRNA Expression
Unique Assay ID:   qhsaLEP0233019
Assay Design:   exonic
Chromosome Location:   chr7:114628567-114628659question
Amplicon Length:   63
Splice Variants Targeted:   ENST00000393491 ENST00000393494 ENST00000634623 ENST00000635109 ENST00000634411 ENST00000440349 ENST00000412402 ENST00000441290 ENST00000635638 ENST00000403559 ENST00000350908 ENST00000393498 ENST00000459666 ENST00000393489 ENST00000390668 ENST00000452963 ENST00000360232 ENST00000635534 ENST00000378237 ENST00000393495 ENST00000408937
LNCipedia Splice Variants Targeted:   lnc-MDFIC-7:6 lnc-MDFIC-7:5 lnc-MDFIC-7:4 lnc-MDFIC-7:3

Gene Information

This gene encodes a member of the forkhead/winged-helix (FOX) family of transcription factors. It is expressed in fetal and adult brain as well as in several other organs such as the lung and gut. The protein product contains a FOX DNA-binding domain and a large polyglutamine tract and is an evolutionarily conserved transcription factor which may bind directly to approximately 300 to 400 gene promoters in the human genome to regulate the expression of a variety of genes. This gene is required for proper development of speech and language regions of the brain during embryogenesis and may be involved in a variety of biological pathways and cascades that may ultimately influence language development. Mutations in this gene cause speech-language disorder 1 (SPCH1) also known as autosomal dominant speech and language disorder with orofacial dyspraxia. Multiple alternative transcripts encoding different isoforms have been identified in this gene.[provided by RefSeq Feb 2010]

Gene Symbol:   FOXP2
Gene Name:   forkhead box P2
Aliases:   CAGH44, DKFZp686H1726, SPCH1, TNRC10
RefSeq:   NC_000007.13 NT_007933.15 NG_007491.2
Ensembl:   ENSG00000128573
LNCipedia:   lnc-MDFIC-7
Entrez:   93986
Chromosome Mapping:   7q31
Gene Strand:   Not Available

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