PrimePCR™ Probe Assay: Abcd3, Mouse

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qMmuCEP0055266
Assay Design:   exonic
Chromosome Location:   3:121779565-121779669question
Amplicon Length:   75
Splice Variants Targeted:   ENSMUST00000029770

Gene Information

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1 MDR/TAP MRP ALD OABP GCN20 White). This protein is a member of the ALD subfamily which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. This peroxisomal membrane protein likely plays an important role in peroxisome biogenesis. Mutations have been associated with some forms of Zellweger syndrome a heterogeneous group of peroxisome assembly disorders. [provided by RefSeq Jul 2008]

Gene Symbol:   Abcd3
Gene Name:   ATP-binding cassette, sub-family D (ALD), member 3
Aliases:   AI313901, AU018866, AW146054, PMP68, PMP70, Pxmp1
RefSeq:   NC_000069.6 NT_039240.8
Ensembl:   ENSMUSG00000028127
Entrez:   19299
Chromosome Mapping:   3 G-H1|3 56.6 cM

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