PrimePCR™ Probe Assay: Abcb1b, Mouse

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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PrimePCR™ PreAmp for Probe Assay: Abcb1b, Mouse
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: Abcb1b, Mouse
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qMmuCEP0055974
Assay Design:   exonic
Chromosome Location:   5:8865881-8865978question
Amplicon Length:   68
Splice Variants Targeted:   ENSMUST00000009058

Gene Information

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1 MDR/TAP MRP ALD OABP GCN20 White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. This gene encodes a membrane glycoprotein which confers a multidrug-resistance phenotype. The protein encoded by the human gene is an ATP-dependent drug efflux pump for xenobiotic compounds which is responsible for decreased drug accumulation in multidrug-resistant cells and mediates the development of resistance to anticancer drugs. [provided by RefSeq Jul 2008]

Gene Symbol:   Abcb1b
Gene Name:   ATP-binding cassette, sub-family B (MDR/TAP), member 1B
Aliases:   Abcb1, Mdr1, Mdr1b, Pgy-1, Pgy1, mdr
RefSeq:   NC_000071.6 NT_039299.7
Ensembl:   ENSMUSG00000028970
Entrez:   18669
Chromosome Mapping:   5 1.0 cM

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