PrimePCR™ Probe Assay: Mc4r, Mouse

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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PrimePCR™ PreAmp for Probe Assay: Mc4r, Mouse
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: Mc4r, Mouse
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qMmuCEP0058290
Assay Design:   exonic
Chromosome Location:   18:66859335-66859432question
Amplicon Length:   68
Splice Variants Targeted:   ENSMUST00000057942

Gene Information

This gene encodes a member of the melanocortin receptor family. Melanocortin receptors are transmembrane G-protein coupled receptors which respond to small peptide hormones and exhibit diverse functions and tissue type localization. As part of the central nervous melanocortin system the encoded protein is competitively bound by either melanocyte stimulating hormone or agouti-related protein to regulate energy homeostasis. Disruption of this gene promotes hyperphagia and obesity and is associated with increased cholesterol levels and insulin resistance. [provided by RefSeq Dec 2012]

Gene Symbol:   Mc4r
Gene Name:   Melanocortin 4 receptor
Aliases:   Fatboy, Glu3
RefSeq:   NC_000084.6 NT_039674.8
Ensembl:   ENSMUSG00000047259
Entrez:   17202
Chromosome Mapping:   18 E1|18

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