PrimePCR™ Probe Assay: Abcc2, Mouse

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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PrimePCR™ PreAmp for Probe Assay: Abcc2, Mouse
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: Abcc2, Mouse
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qMmuCIP0031432
Assay Design:   Intron-spanning
Chromosome Location:   19:43782398-43784278question
Amplicon Length:   102
Splice Variants Targeted:   ENSMUST00000026208

Gene Information

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1 MDR/TAP MRP ALD OABP GCN20 White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions in the canalicular surface of the hepatocyte and in biliary transport and appears to contribute to drug resistance in mammalian cells. Several different mutations in the human gene have been observed in patients with Dubin-Johnson syndrome (DJS) an autosomal recessive disorder characterized by conjugated hyperbilirubinemia. Alternative splice variants have been observed for this gene; however they have not been fully described. [provided by RefSeq Jul 2008]

Gene Symbol:   Abcc2
Gene Name:   ATP-binding cassette, sub-family C (CFTR/MRP), member 2
Aliases:   AI173996, Abc30, Cmoat, Mrp2, cMRP
RefSeq:   NC_000085.6 NT_039687.8
Ensembl:   ENSMUSG00000025194
Entrez:   12780
Chromosome Mapping:   19 C3|19 43.0 cM

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