PrimePCR™ Probe Assay: Abcc1, Mouse

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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PrimePCR™ PreAmp for Probe Assay: Abcc1, Mouse
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: Abcc1, Mouse
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qMmuCIP0033145
Assay Design:   Intron-spanning
Chromosome Location:   16:14389884-14391368question
Amplicon Length:   160
Splice Variants Targeted:   ENSMUST00000100167 ENSMUST00000154748 ENSMUST00000134776 ENSMUST00000144676

Gene Information

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1 MDR/TAP MRP ALD OABP GCN20 White). This full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. This protein plays an essential role in the defense against toxic compounds and serves as the major high-affinity transporter of leukotriene C4. The encoded protein may also play an essential role in steroid hormone homeostasis as a transporter for steroid hormones and their metabolites. [provided by RefSeq Nov 2011]

Gene Symbol:   Abcc1
Gene Name:   ATP-binding cassette, sub-family C (CFTR/MRP), member 1
Aliases:   Abcc1a, Abcc1b, MRP, Mdrap, Mrp1
RefSeq:   NC_000082.6 NT_039624.8
Ensembl:   ENSMUSG00000023088
Entrez:   17250
Chromosome Mapping:   16 A1|16

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