PrimePCR™ Probe Assay: Itgb4, Mouse

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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PrimePCR™ PreAmp for Probe Assay: Itgb4, Mouse
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: Itgb4, Mouse
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qMmuCIP0033533
Assay Design:   Intron-spanning
Chromosome Location:   11:115993407-115994337question
Amplicon Length:   96
Splice Variants Targeted:   ENSMUST00000021107 ENSMUST00000106460 ENSMUST00000068981 ENSMUST00000106458 ENSMUST00000106461 ENSMUST00000169928

Gene Information

Integrins are heterodimers comprised of alpha and beta subunits that are noncovalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion and transduced signals that regulate gene expression and cell growth. This gene encodes the integrin beta 4 subunit a receptor for the laminins. This subunit tends to associate with alpha 6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq Jul 2008]

Gene Symbol:   Itgb4
Gene Name:   Integrin beta 4
Aliases:   AA407042, C230078O20, CD104
RefSeq:   NC_000077.6 NT_096135.6
Ensembl:   ENSMUSG00000020758
Entrez:   192897
Chromosome Mapping:   11 E2|11 76.0 cM

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