Gene:  ABCC8, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1 MDR/TAP MRP ALD OABP GCN20 White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a modulator of ATP-sensitive potassium channels and insulin release. Mutations and deficiencies in this protein have been observed in patients with hyperinsulinemic hypoglycemia of infancy an autosomal recessive disorder of unregulated and high insulin secretion. Mutations have also been associated with non-insulin-dependent diabetes mellitus type II an autosomal dominant disease of defective insulin secretion. Alternative splicing of this gene has been observed; however the transcript variants have not been fully described. [provided by RefSeq Jul 2008]

PrimePCR™ SYBR® Green Assay: ABCC8, Human
ATP-binding cassette, sub-family C (CFTR/MRP), member 8

Assay Type: SYBR® Green
Assay Design: Exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0001031
Info:   Recommended - best coverage
List Price:    $146.00
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PrimePCR™ SYBR® Green Assay: ABCC8, Human
ATP-binding cassette, sub-family C (CFTR/MRP), member 8

Assay Type: SYBR® Green
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0041912
Info:   Same primer pair as used in probe assay qHsaCEP0049175
List Price:    $146.00
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PrimePCR™ Probe Assay: ABCC8, Human
ATP-binding cassette, sub-family C (CFTR/MRP), member 8

Assay Type: Probe
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0049175
List Price:    $214.00
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