Gene:  APAF1, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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This gene encodes a cytoplasmic protein that initiates apoptosis. This protein contains several copies of the WD-40 domain a caspase recruitment domain (CARD) and an ATPase domain (NB-ARC). Upon binding cytochrome c and dATP this protein forms an oligomeric apoptosome. The apoptosome binds and cleaves caspase 9 preproprotein releasing its mature activated form. Activated caspase 9 stimulates the subsequent caspase cascade that commits the cell to apoptosis. Alternative splicing results in several transcript variants encoding different isoforms. [provided by RefSeq Jul 2008]

PrimePCR™ SYBR® Green Assay: APAF1, Human
apoptotic peptidase activating factor 1

Assay Type: SYBR® Green
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0043883
Info:   Recommended - best coverage; Same primer pair as used in probe assay qHsaCEP0051145
List Price:    $153.00
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PrimePCR™ SYBR® Green Assay: APAF1, Human
apoptotic peptidase activating factor 1

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0008058
List Price:    $153.00
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PrimePCR™ Probe Assay: APAF1, Human
apoptotic peptidase activating factor 1

Assay Type: Probe
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0051145
List Price:    $225.00
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