Gene:  APEX2, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This gene encodes a protein shown to have a weak class II AP endonuclease activity. Most of the encoded protein is located in the nucleus but some is also present in mitochondria. This protein may play an important role in both nuclear and mitochondrial base excision repair (BER). [provided by RefSeq Jul 2008]

PrimePCR™ SYBR® Green Assay: APEX2, Human
APEX nuclease (apurinic/apyrimidinic endonuclease) 2

Assay Type: SYBR® Green
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0046611
Info:   Same primer pair as used in probe assay qHsaCEP0053872
List Price:    $174.00
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PrimePCR™ SYBR® Green Assay: APEX2, Human
APEX nuclease (apurinic/apyrimidinic endonuclease) 2

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0014167
Info:   Recommended - best efficiency
List Price:    $174.00
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PrimePCR™ Probe Assay: APEX2, Human
APEX nuclease (apurinic/apyrimidinic endonuclease) 2

Assay Type: Probe
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0053872
List Price:    $255.00
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