Gene:  CASP4, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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This gene encodes a protein that is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain and a large and small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits. This caspase is able to cleave and activate its own precursor protein as well as caspase 1 precursor. When overexpressed this gene induces cell apoptosis. Alternative splicing results in transcript variants encoding distinct isoforms. [provided by RefSeq Jul 2008]

PrimePCR™ SYBR® Green Assay: CASP4, Human
caspase 4, apoptosis-related cysteine peptidase

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0018365
Info:   Same primer pair as used in probe assay qHsaCIP0031810
List Price:    $146.00
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PrimePCR™ Probe Assay: CASP4, Human
caspase 4, apoptosis-related cysteine peptidase

Assay Type: Probe
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCIP0031810
List Price:    $214.00
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