Gene:  CSH1, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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The protein encoded by this gene is a member of the somatotropin/prolactin family of hormones and plays an important role in growth control. The gene is located at the growth hormone locus on chromosome 17 along with four other related genes in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. Although the five genes share a remarkably high degree of sequence identity they are expressed selectively in different tissues. Alternative splicing generates additional isoforms of each of the five growth hormones leading to further diversity and potential for specialization. This particular family member is expressed mainly in the placenta and utilizes multiple transcription initiation sites. Expression of the identical mature proteins for chorionic somatomammotropin hormones 1 and 2 is upregulated during development although the ratio of 1 to 2 increases by term. Mutations in this gene result in placental lactogen deficiency and Silver-Russell syndrome. [provided by RefSeq Jul 2008]

PrimePCR™ SYBR® Green Assay: CSH1, Human
chorionic somatomammotropin hormone 1 (placental lactogen)

Assay Type: SYBR® Green
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0038929
Info:   Same primer pair as used in probe assay qHsaCEP0041651
List Price:    $174.00
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PrimePCR™ Probe Assay: CSH1, Human
chorionic somatomammotropin hormone 1 (placental lactogen)

Assay Type: Probe
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0041651
List Price:    $255.00
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