Gene:  CYBB, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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Cytochrome b (-245) is composed of cytochrome b alpha (CYBA) and beta (CYBB) chain. It has been proposed as a primary component of the microbicidal oxidase system of phagocytes. CYBB deficiency is one of five described biochemical defects associated with chronic granulomatous disease (CGD). In this disorder there is decreased activity of phagocyte NADPH oxidase; neutrophils are able to phagocytize bacteria but cannot kill them in the phagocytic vacuoles. The cause of the killing defect is an inability to increase the cell's respiration and consequent failure to deliver activated oxygen into the phagocytic vacuole. [provided by RefSeq Jul 2008]

PrimePCR™ SYBR® Green Assay: CYBB, Human
cytochrome b-245, beta polypeptide

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0015139
Info:   Same primer pair as used in probe assay qHsaCIP0029732
List Price:    $164.00
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PrimePCR™ Probe Assay: CYBB, Human
cytochrome b-245, beta polypeptide

Assay Type: Probe
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCIP0029732
List Price:    $241.00
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