Gene:  HLA-DMB, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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HLA-DMB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DMA) and a beta (DMB) chain both anchored in the membrane. It is located in intracellular vesicles. DM plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP (class II-associated invariant chain peptide) molecule from the peptide binding site. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes dendritic cells macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide exons 2 and 3 encode the two extracellular domains exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. [provided by RefSeq Jul 2008]

PrimePCR™ SYBR® Green Assay: HLA-DMB, Human
major histocompatibility complex, class II, DM beta

Assay Type: SYBR® Green
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0037503
Info:   Same primer pair as used in probe assay qHsaCEP0040226
List Price:    $174.00
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PrimePCR™ Probe Assay: HLA-DMB, Human
major histocompatibility complex, class II, DM beta

Assay Type: Probe
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0040226
List Price:    $255.00
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