Gene:  IDO1, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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PrimePCR
Lookup Tool
Design and Validation of Real-Time PCR Primers-test
Pathway Curation
and Array Design Strategy
Control and Reference Assays for Real-Time PCR

This gene encodes indoleamine 23-dioxygenase (IDO) - a heme enzyme that catalyzes the first and rate-limiting step in tryptophan catabolism to N-formyl-kynurenine. This enzyme acts on multiple tryptophan substrates including D-tryptophan L-tryptophan 5-hydroxy-tryptophan tryptamine and serotonin. This enzyme is thought to play a role in a variety of pathophysiological processes such as antimicrobial and antitumor defense neuropathology immunoregulation and antioxidant activity. Through its expression in dendritic cells monocytes and macrophages this enzyme modulates T-cell behavior by its peri-cellular catabolization of the essential amino acid tryptophan.[provided by RefSeq Feb 2011]

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My PrimePCR Hot List stores your saved PrimePCR products and configurations

My PrimePCR Hot List stores your saved PrimePCR products and configurations

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My PrimePCR Hot List stores your saved PrimePCR products and configurations

My PrimePCR Hot List stores your saved PrimePCR products and configurations

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My PrimePCR Hot List stores your saved PrimePCR products and configurations

My PrimePCR Hot List stores your saved PrimePCR products and configurations

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