Gene:  S100B, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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Lookup Tool
Design and Validation of Real-Time PCR Primers-test
Pathway Curation
and Array Design Strategy
Control and Reference Assays for Real-Time PCR

The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21; however this gene is located at 21q22.3. This protein may function in Neurite extension proliferation of melanoma cells stimulation of Ca2+ fluxes inhibition of PKC-mediated phosphorylation astrocytosis and axonal proliferation and inhibition of microtubule assembly. Chromosomal rearrangements and altered expression of this gene have been implicated in several neurological neoplastic and other types of diseases including Alzheimer's disease Down's syndrome epilepsy amyotrophic lateral sclerosis melanoma and type I diabetes. [provided by RefSeq Jul 2008]

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My PrimePCR Hot List stores your saved PrimePCR products and configurations

My PrimePCR Hot List stores your saved PrimePCR products and configurations

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My PrimePCR Hot List stores your saved PrimePCR products and configurations

My PrimePCR Hot List stores your saved PrimePCR products and configurations

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My PrimePCR Hot List stores your saved PrimePCR products and configurations

My PrimePCR Hot List stores your saved PrimePCR products and configurations

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