Gene:  TAP2, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1 MDR/TAP MRP ALD OABP GCN20 White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. This gene is located 7 kb telomeric to gene family member ABCB2. The protein encoded by this gene is involved in antigen presentation. This protein forms a heterodimer with ABCB2 in order to transport peptides from the cytoplasm to the endoplasmic reticulum. Mutations in this gene may be associated with ankylosing spondylitis insulin-dependent diabetes mellitus and celiac disease. Alternative splicing of this gene produces two products which differ in peptide selectivity and level of restoration of surface expression of MHC class I molecules. [provided by RefSeq Jul 2008]

PrimePCR™ SYBR® Green Assay: TAP2, Human
transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)

Assay Type: SYBR® Green
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0037295
Info:   Same primer pair as used in probe assay qHsaCEP0040018
List Price:    $146.00
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PrimePCR™ Probe Assay: TAP2, Human
transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)

Assay Type: Probe
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0040018
List Price:    $214.00
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