Gene:  C2, Human

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Component C2 is a serum glycoprotein that functions as part of the classical pathway of the complement system. Activated C1 cleaves C2 into C2a and C2b. The serine proteinase C2a then combines with complement factor 4b to create the C3 or C5 convertase. Deficiency of C2 has been reported to associated with certain autoimmune diseases and SNPs in this gene have been associated with altered susceptibility to age-related macular degeneration. This gene localizes within the class III region of the MHC on the short arm of chromosome 6. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described in publications but their full-length sequence has not been determined.[provided by RefSeq Mar 2009]

PrimePCR™ SYBR® Green Assay: C2, Mouse
Complement component 2 (within H-2S)

Assay Type: SYBR® Green
Assay Design: Exonic
Application: Gene Expression
Unique Assay ID: qMmuCED0024621
List Price:    $174.00
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PrimePCR™ SYBR® Green Assay: C2, Mouse
Complement component 2 (within H-2S)

Assay Type: SYBR® Green
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qMmuCED0046794
Info:   Recommended - best coverage; Same primer pair as used in probe assay qMmuCEP0055220
List Price:    $174.00
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PrimePCR™ Probe Assay: C2, Mouse
Complement component 2 (within H-2S)

Assay Type: Probe
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qMmuCEP0055220
List Price:    $255.00
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