Gene:  Cldn2, Mouse

PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets and also play critical roles in maintaining cell polarity and signal transductions. The knockout mice lacking this gene display normal appearance activity growth and behavior but are defective in the leaky and cation-selective paracellular permeability properties of renal proximal tubules. The proteins encoded by this gene and another family member Cldn12 are also critical for vitamin D-dependent Ca2+ absorption between enterocytes. [provided by RefSeq Aug 2010]

PrimePCR™ SYBR® Green Assay: Cldn2, Rat
Claudin 2

Assay Type: SYBR® Green
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qRnoCED0006461
List Price:    $174.00
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PrimePCR™ Probe Assay: Cldn2, Rat
Claudin 2

Assay Type: Probe
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qRnoCEP0028292
List Price:    $255.00
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