PrimePCR™ Probe Assay: PAK2, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0058392
Assay Design:   exonic
Chromosome Location:   3:196558354-196558485question
Amplicon Length:   102
Splice Variants Targeted:   ENST00000327134

Gene Information

The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins CDC42 and RAC1 and have been implicated in a wide range of biological activities. The protein encoded by this gene is activated by proteolytic cleavage during caspase-mediated apoptosis and may play a role in regulating the apoptotic events in the dying cell. [provided by RefSeq Jul 2008]

Gene Symbol:   PAK2
Gene Name:   p21 protein (Cdc42/Rac)-activated kinase 2
Aliases:   PAK65, PAKgamma
RefSeq:   NC_000003.11 NG_009227.1 NT_029928.13
Ensembl:   ENSG00000180370
Entrez:   5062
Chromosome Mapping:   3q29

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