PrimePCR™ Probe Assay: CCL21, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0024827
Assay Design:   Exonic
Chromosome Location:   9:34709783-34709998question
Amplicon Length:   83
Splice Variants Targeted:   ENST00000259607 ENST00000378792

Gene Information

This gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. Similar to other chemokines the protein encoded by this gene inhibits hemopoiesis and stimulates chemotaxis. This protein is chemotactic in vitro for thymocytes and activated T cells but not for B cells macrophages or neutrophils. The cytokine encoded by this gene may also play a role in mediating homing of lymphocytes to secondary lymphoid organs. It is a high affinity functional ligand for chemokine receptor 7 (CCR7) that is expressed on T and B lymphocytes and a known receptor for another member of the cytokine family (small inducible cytokine A19). [provided by RefSeq Jul 2008]

Gene Symbol:   CCL21
Gene Name:   chemokine (C-C motif) ligand 21
Aliases:   6Ckine, CKb9, ECL, MGC34555, SCYA21, SLC, TCA4
RefSeq:   NC_000009.11 NT_008413.18
Ensembl:   ENSG00000137077
Entrez:   6366
Chromosome Mapping:   9p13

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